Use Dependent Attenuation of Rat HCN1-Mediated Ih in Intact HEK293 Cells
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چکیده
منابع مشابه
Use Dependent Attenuation of Rat HCN1-Mediated Ih in Intact HEK293 Cells.
BACKGROUND/AIMS Cationic currents (Ih) through the fast activating and relatively cAMP insensitive subtype of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, HCN1, are limited by cytosolic factors in mammalian cells. This cytosolic HCN1 break is boosted by changes in membrane voltage that are not characterized on a biophysical level, yet. METHODS We overexpressed rat (r)HC...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2016
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000445566